C-terminal Alternative Splicing Modulates Single-Channel Gating of Cav1.3 L-Type Calcium Channel
نویسندگان
چکیده
منابع مشابه
C-Terminal alternative splicing changes the gating properties of a human spinal cord calcium channel alpha 1A subunit.
The calcium channel alpha(1A) subunit gene codes for proteins with diverse structure and function. This diversity may be important for fine tuning neurotransmitter release at central and peripheral synapses. The alpha(1A) C terminus, which serves a critical role in processing information from intracellular signaling molecules, is capable of undergoing extensive alternative splicing. The purpose...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2010
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2009.12.2806